Real Madrid beat Leganes 2-1 in La Liga on Saturday after coach Zinedine Zidane heavily rotated his side in preparation for Tuesday's Champions League semi-final second leg against Bayern Munich, including leaving out top-scorer Cristiano Ronaldo.
Holders Barcelona reached the King's Cup semi-finals with a 2-0 win over Espanyol on Thursday to overcome a first-leg deficit on a night when new signing Philippe Coutinho made his debut.
Barcelona won their 26th King's Cup when two goals from Pedro and one from Lionel Messi gave them a 3-0 victory over Athletic Bilbao in coach Pep Guardiola's final match in charge on Friday.
Real, who have smashed the La Liga scoring record, clinched their 32nd league crown and their first in four years when Gonzalo Higuain, Mesut Ozil and Cristiano Ronaldo struck in a frenetic 3-0 win at 10-man Athletic Bilbao on Wednesday.
News of all that's transpired on and off the football field
IMAGES from the Europa League matches played on Thursday
La Liga leaders Barcelona were held to a 2-2 home draw by Celta Vigo on Saturday as their former assistant coach Juan Carlos Unzue dented the title hopes of the Catalans, who dropped points for the second game in a row for the first time this campaign.
Real Madrid forward Gareth Bale has been ruled out of Saturday's La Liga game at Athletic Bilbao, coach Zinedine Zidane said on Friday, after the Wales international picked up yet another injury on his return to action on Tuesday after 63 days out.
Athletic Bilbao's bid for a berth in next season's Europa League stuttered when they lost 2-1 at Espanyol on Monday.
Athletic Bilbao ended tiny Mirandes's remarkable run with a ruthless 6-2 win in their King's Cup semi-final second leg on Tuesday to set up a final with either Barcelona or Valencia.
Borussia Dortmund snatched a late goal at Atalanta to progress with a 1-1 draw, while AC Milan and Atletico Madrid, both with three-goal leads from the away legs, completed the formality of qualifying with 1-0 wins at home on Thursday.
Atletico Madrid striker Antoine Griezmann struck twice as the Spanish side outclassed hapless Olympique de Marseille 3-0 on Wednesday to win the Europa League for the third time.
Marcelino dismissed but Valencia keep pressure on Barcelona
Napoli went down 3-1 at home to RB Leipzig, Arsenal and AC Milan enjoyed comfortable away wins, and Borussia Dortmund's Michy Batshuayi scored twice to secure a 3-2 victory in Europa League last 32, first leg action
The victory saw the unfashionable Madrid club tighten their grip on the coveted fourth spot in the table by moving on to 58 points after 36 games, three points clear of nearest challengers Sevilla, who lost to Leganes on Friday.
World Champion Viswanthan Anand defeated Francisco Vallejo Pons of Spain in the 10th and final round to avoid a last-place finish at the fourth Final Masters chess tournament in Bilbao.
World Champion Viswanathan Anand was shocked by Levon Aronian of Armenia in the ninth and penultimate round of the fourth Final Masters as he slipped to the last spot with just one round to go in the category-22 super tournament in Bilbao.
Real Sociedad's Inigo Martinez scored from inside his own half in the Basque derby on Sunday, but Fernando Llorente's brace made sure Athletic Bilbao earned a 2-1 away win in La Liga.
World Champion Viswanathan Anand has slipped to joint third spot after he was held to a draw by Levon Aronian of Armenia at the half way stage of the fourth Bilbao Final Masters.
A new-look Atletico Madrid suffered a setback in their opening La Liga match of the season when they squandered several chances and twice struck the post in a 0-0 home draw with Osasuna on Sunday.
Ibrahimovic has not played since suffering a career-threatening knee ligament injury in United's Europa League quarter-final second leg match against Anderlecht at Old Trafford in April.
The Champions League quarter-final between Liverpool and Manchester City is one of the most anticipated games of the season pitting the Premier League's runaway leaders against the top scorers in Europe's elite competition.
Real Madrid suffered a shock 1-0 home defeat to Real Betis on Wednesday as an inspired performance from their former goalkeeper Antonio Adan and a stoppage-time winner from Antonio Sanabria stunned the Liga champions.
It is a scenario few could have foreseen after Real won a Liga and Champions League double last term and began this season so convincingly.
News of all that's transpired on and off the football field
Athletic Bilbao boosted their chances of securing a place in next season's Europa League when they fought back from a goal and a man down to snatch a 2-1 victory at struggling Osasuna on Sunday.
AC Milan, Villarreal and Nice reached the knockout stage of the Europa League after posting wins on Thursday in the penultimate round of the group stage.
Athletic Bilbao forward Urko Vera netted his first La Liga goal deep into added time to snatch a 2-2 draw for the Basque club at Getafe on Monday.
IMAGES from La Liga matches played on Sunday
Manchester City failed in an audacious transfer deadline day move for Leicester City midfielder Riyadh Mahrez, British media reported on Wednesday.
Lionel Messi scored his 12th league goal of the season but Barcelona had to rely on exceptional saves from Marc-Andre ter Stegen as they rode their luck to win 2-0 at Athletic Bilbao on Saturday and stay four points clear at the top of La Liga.
Former UEFA Cup winners Anderlecht reached the Europa League knockout stage with the only perfect record on Thursday and were joined in the last 32 by Athletic Bilbao, Legia Warsaw, PSV Eindhoven and Twente Enschede with two games to spare.
Chelsea agreed a deal to sign Real Madrid striker Alvaro Morata, subject to the Spain international agreeing personal terms and passing a medical.
A Marco Asensio-inspired Real Madrid crushed Eibar 3-0 to close the gap on La Liga leaders Barcelona to five points on Sunday, with Karim Benzema starting on the bench.
Athletic Bilbao survived a constant state of siege to hold a weakened Barcelona to a 0-0 draw at the Nou Camp in a King's Cup last 16 first-leg match on Tuesday. La Liga leaders Barca had won 10 successive games in all competitions, scoring 31 goals in the last seven, but they ran out of ideas against their resolute Basque visitors.
A summary of Thursday's matches in Europe's second tier club football tournament
World champion Viswanathan Anand could do little with his white pieces as he settled for a draw with world number one Magnus Carlsen in the first round of the fourth Bilbao Final Masters, in Sao Paulo, Brazil.
World Champion Viswanathan Anand split the point with leader Vladimir Kramnik of Russia to remain second after the end of the fifth and penultimate round of Bilbao Final Masters chess tournament.
La Liga paupers Levante held big-spending visitors Real Madrid to a 0-0 draw on Saturday which is bound to put more pressure on new coach Jose Mourinho.
Fernando Llorente netted a dramatic late winner for Athletic Bilbao to eliminate Sporting and Atletico Madrid comfortably held on to a first-leg lead to oust La Liga rivals Valencia on Thursday and set up an all-Spanish Europa League final.